专业监测看板

Comparative Clinical Study Between Virtual Reality Hypnosis and Nitrous Oxide Inhalation for Dental Anxie

药物 / 成分：Nitrous Oxide inhalation、Dispositif de RV - HYPNO VR

登记的停止原因（原文）：inclusion challenges

Study of the RNR Inhibitor BBI-825 in Subjects With Tumors With Resistance Gene Amplifications

药物 / 成分：BBI-825

登记的停止原因（原文）：Strategic decision made following an assessment of preliminary PK data from the Part 1 portion of the trial showing a lack of dose proportional exposure and the increasing complexity and associated development costs in this landscape.

To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and Bezafibrate

药物 / 成分：FDC tablet (OCA 5 mg + BZF 400 mg SR)

登记的停止原因（原文）：Intercept made a business decision to terminate the study based on FDA's request for voluntary withdrawal of Ocaliva and the issuance of clinical hold on studies under US IND involving OCA.

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

药物 / 成分：Aticaprant、Placebo

登记的停止原因（原文）：Early study termination due to insufficient efficacy.

Study of Obeldesivir to Treat Children With Respiratory Syncytial Virus (RSV) Infection

药物 / 成分：Obeldesivir、Obeldesivir Placebo

登记的停止原因（原文）：Study was terminated by Sponsor; the decision was not due to any safety findings.

Providing "Good Sleep" for ICU Sedation

药物 / 成分：Normal saline infusion、Dexmedetomidine、Propofol

登记的停止原因（原文）：Lack of funding

Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

药物 / 成分：Azacitidine、Venetoclax

登记的停止原因（原文）：\<75% participation

Safety & Efficacy of Consolidative Hypofractionated Radiation Therapy for Boosting Residual Lung Cancer With Durvalumab

药物 / 成分：consolidative hypofractionated radiation therapy (hfRT)、Durvalumab 50 MG/ML

登记的停止原因（原文）：Poor accrual

Cyclops Syndrome After Anterior Cruciate Ligament Reconstruction

药物 / 成分：Botulinum toxin、Placebo

登记的停止原因（原文）：The site had difficulties to recruit. Some associated investigators can not be involved in the study anymore and others centers contacted don't have enough ressources to conduct the study. Premature end of inclusions on 07/10/2025 \& LPLV on11/27/2025

Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site

药物 / 成分：Atezolizumab、Radiation Therapy、Therapeutic Conventional Surgery

登记的停止原因（原文）：Slow accrual

A Study to Investigate Use of Off-the-shelf Natural Killer (NK) Cells (SAR445419) in Relapsed/Refractory Acute Myeloid Leukemia

药物 / 成分：SAR445419、fludarabine、cytarabine

登记的停止原因（原文）：Sponsor's decision

Clinical Study of CAR-T Cell Therapy Following ASCT for R/R B-cell Non-Hodgkin's Lymphoma

药物 / 成分：Apheresis、Autologous Stem Cell Transplantation、CAR-T Cell Therapy

登记的停止原因（原文）：The study was terminated due to changes in national policy.

An Efficacy and Safety Study of Tramadol/Acetaminophen Versus Diclofenac in the Treatment of Pain in Participants With Ankylosing Spondylitis Receiving Stable Treatment of Disease Modifying Anti-rheumatic Drugs (DMARDs)

药物 / 成分：Tramadol /acetaminophen、Diclofenac

A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's Sarcoma

药物 / 成分：everolimus

登记的停止原因（原文）：results from interim analysis conducted to study interruption

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

药物 / 成分：Remifentanil、Remifentanil+ Placebo、Remifentanil +ultra-low dose naloxone

登记的停止原因（原文）：Study terminated early due to low enrollment. Only 8 participants enrolled out of the target 105.

A Study to Evaluate Concurrent VRP-HER2 Vaccination and Pembrolizumab for Patients With Breast Cancer

药物 / 成分：VRP-HER2、Pembrolizumab

登记的停止原因（原文）：Enrollment issue

Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%

药物 / 成分：SMT + PE-A 5%、Standard Medical Treatment

登记的停止原因（原文）：Due to corporate business reasons only (non-safety related decision)

Avoiding Neuromuscular Blockers to Reduce Complications

药物 / 成分：Neuromuscular Blocking Agents、Anesthetic Adjuncts

登记的停止原因（原文）：Study terminated due to lack of enrollment.

ESP Block for Laparoscopic Nephrectomy Surgeries

药物 / 成分：Ropivacaine injection、Sham

登记的停止原因（原文）：It was terminated because of poor recruitment rate.

A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML)

药物 / 成分：Venetoclax、Azacitidine、Best Supportive Care (BSC)

登记的停止原因（原文）：Strategic considerations