专业监测看板

Modulation of Motor Learning Via tDCS in a Dexterous Video Game Task

药物 / 成分：tDCS

登记的停止原因（原文）：Interim study results were not favorable to continue with further enrollment

Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

药物 / 成分：Cladribine, Cytarabine, Mitoxantrone, G-CSF (CLAG-M) regimen、Cladribine and Cytarabine (CLLDAC) Regimen

登记的停止原因（原文）：No longer have funding support to complete the pharmacogenetics component.

Vancomycin for Primary Sclerosing Cholangitis

药物 / 成分：Vancomycin、Placebo

登记的停止原因（原文）：Funding terminated

The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )

药物 / 成分：vitamin D3

登记的停止原因（原文）：Enrollment stopped at 55 of 316 planned participants due to recruitment challenges related to the COVID-19 pandemic and funding constraints. All enrolled participants completed 52-week follow-up.

FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer

药物 / 成分：Digoxin、5Fluorouracil、Calcium Leucovorin、Irinotecan

登记的停止原因（原文）：Due to low accrual and futility

Factor In the Initial Resuscitation of Severe Trauma 2 Patients

药物 / 成分：Fibrinogen + PCC、Frozen Plasma

登记的停止原因（原文）：Upon IDSMC's review of interim data, they recommended the trial be stopped based on futility.

Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS

药物 / 成分：MT-1186、Placebo

登记的停止原因（原文）：Futility Analysis of parent study MT-1186-A02 was met.

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

药物 / 成分：JDQ443、trametinib、Ribociclib、cetuximab

登记的停止原因（原文）：Business reasons and not based on any safety concerns.

A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic Solid Tumors (MK-1484-001)

药物 / 成分：MK-1484、Pembrolizumab

登记的停止原因（原文）：Business Reasons

A Study to Assess the Adverse Events and How Intravenously Infused Livmoniplimab in Combination With Budigalimab Moves Through the Bodies of Adult Chinese Participants With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC)

药物 / 成分：Livmoniplimab、Budigalimab

登记的停止原因（原文）：Strategic considerations

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

药物 / 成分：SAR441566、SAR441566 matching Placebo

登记的停止原因（原文）：Business decision

Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions

药物 / 成分：ePRO Application

登记的停止原因（原文）：Grant Terminated by Sponsor

Peripheral Nerve Stimulation Therapy for Atrial Fibrillation

药物 / 成分：Wrist Device、Ear Device、Sham Device

登记的停止原因（原文）：The Sponsor and Principal Investigator have mutually agreed to initiate study closure due to prolonged recruitment challenges that have prevented the trial from meeting its enrollment milestones within the projected study timeline.

Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease

药物 / 成分：Computerized Cognitive Training、Active tDCS (tDCS) on DLPFC

登记的停止原因（原文）：Lack of funding

Psoas Tenotomy Under Ultrasound

药物 / 成分：Psoas tenotomy under ultrasound

登记的停止原因（原文）：Failure of the surgical procedure under investigation to achieve satisfactory results.

PREMEDICAL is a Clinical Investigation Aiming to Create a Data Basis That Can be Used to Enrich Information Collected in the Course of the Classic Patient Journey. Patients in the Emergency Department Will be Asked to Answer Patient-related and Symptom-oriented Questions. Minimum Age is 18 Years

登记的停止原因（原文）：Funding issues, recruitment targets not met

Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

药物 / 成分：Atezolizumab、DEC-205/NY-ESO-1 Fusion Protein CDX-1401、Guadecitabine、Laboratory Biomarker Analysis

登记的停止原因（原文）：The study was terminated due to a shortage of the drug supply.

Phase II Trial of Nivolumab Plus Ipilimumab in Patients With Renal Medullary Carcinoma

药物 / 成分：Ipilimumab、Nivolumab

登记的停止原因（原文）：The study met its prespecified futility criteria during the prespecified interim futility analysis after enrolling the first cohort of 10 patients.

Anti-VEGF Therapy for Acute Thyroid Eye Disease

药物 / 成分：Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept、Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept、Sub-tenon injection of hyaluronidase (HA) alone

登记的停止原因（原文）：Funding prematurely ended

Impact of Metformin on Immuno-virologic Parameters in HIV

药物 / 成分：Metformin

登记的停止原因（原文）：During the COVID pandemic, our IRB halted enrollment into the study among other changes. Post COVID it was decided that too long an interval between patient enrollment was problematic for the study and a discussion was made to terminate.