专业监测看板

Study of mRNA Vaccine Formulation Against COVID-19 in Healthy Adults 18 Years of Age and Older

药物 / 成分：SARS-CoV-2 mRNA vaccine formulation 1、SARS-CoV-2 mRNA vaccine formulation 2、SARS-CoV-2 mRNA vaccine formulation 3、Placebo (0.9% normal saline)

登记的停止原因（原文）：Sponsor's decision not to pursue further development of this product given the wide availability of authorized/approved mRNA COVID-19 vaccines

Safety and Tolerability Study in Adults With Cold Agglutinin Disease Previously Treated With SAR445088 or Never Treated With SAR445088

药物 / 成分：SAR445088

Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI)

药物 / 成分：SAR439459、Placebo

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LB4330 in Patients With Advanced Solid Tumors（MEETCD8-001）

药物 / 成分：LB4330

登记的停止原因（原文）：Due to adjustments in the sponsor's development strategy, it has been decided to terminate the study.

A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function

药物 / 成分：Intravenous sedation using propofol、Intravenous sedation with midazolam

登记的停止原因（原文）：Difficulty in recruiting

A Study on the Safety and Efficacy of LAE001 in the Treatment of Metastatic Prostate Cancer

药物 / 成分：LAE001

登记的停止原因（原文）：This is phase I/II study, phase I study completed, phase II study started and enrolled 1 patient. Company strategy consideration to terminated phase 2 study finally.

A First-in-Human Dose Escalation and Expansion Study to Evaluate Intratumoral Administration of SAR441000 as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

药物 / 成分：SAR441000、Cemiplimab REGN2810

登记的停止原因（原文）：Sponsor terminated the study for non-safety reasons

Pediatric Concussion Outcomes

药物 / 成分：Nortriptyline、Placebo

登记的停止原因（原文）：The study was stopped prematurely due to a low enrollment rate.

Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant

药物 / 成分：Leflunomide tablet

登记的停止原因（原文）：Issues with recruitment. Practice changes, including leflunomide use for CMV, have led to a lack of musculoskeletal GVHD cases. Only one patient enrolled in the trial will continue treatment as per standard care.

Norepinephrine in Caesarian Section

药物 / 成分：Norepinephrine、Norepinephrine

登记的停止原因（原文）：patient inclusion is too difficult