专业监测看板

KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

药物 / 成分：KYV-101 anti-CD19 CAR-T cell therapy、Standard lymphodepletion regimen

登记的停止原因（原文）：Study discontinued due to sponsor decision.

KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

药物 / 成分：KYV-101 anti-CD19 CAR-T cell therapy、Standard lymphodepletion regimen

登记的停止原因（原文）：Study discontinued due to sponsor decision.

A Study of Auxora in Patients With AKI and Injurious Lung "Crosstalk"

药物 / 成分：Auxora、Placebo

登记的停止原因（原文）：The study was stopped due to imbalance in randomization stratification of severe patients.

KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

药物 / 成分：KYV-101、Standard lymphodepletion regimen

登记的停止原因（原文）：Study discontinued due to sponsor decision

A Study of LY3549492 in Adults With Obesity or Overweight With Type 2 Diabetes

药物 / 成分：LY3549492、Placebo

登记的停止原因（原文）：Study terminated for strategic business reasons

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

药物 / 成分：[225Ac]Ac-A9-3408、[68Ga]Ga-A9T-3202

登记的停止原因（原文）：Due to a strategic decision to re-prioritize the sponsor's existing portfolio.

Randomized, Controlled Trial of Extended-Release Niacin (Niaspan®) to Augment Subacute Ischemic Stroke Recovery

药物 / 成分：Extended-Release Niacin、Placebo

登记的停止原因（原文）：Study was stopped early due to limitations in funding. As a result, the sample size was insufficient for meaningful exploration of functional outcomes

Age and Response to Flu Vaccines

药物 / 成分：Influenza Virus Quadrivalent Inactivated Vaccine、Influenza Virus Quadrivalent Inactivated Vaccine

登记的停止原因（原文）：Study visits could not be completed for all enrolled participants due to COVID-19 Pandemic

A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM)

药物 / 成分：FE 999049、Placebo

登记的停止原因（原文）：The probability of enrolling subjects in the trial in a reasonable timeframe was too low. The termination was not due to safety concerns nor changes in Ferring's Reproductive Medicine strategy or interest in developing treatments for Male Infertility

Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants

药物 / 成分：Valganciclovir、Simple Syrup

登记的停止原因（原文）：Study sponsor closed trial due to slow enrollment.

Optimal Anti-EGFR Treatment of mCRC Patients With Low-Frequency RAS Mutation

药物 / 成分：Panitumumab、Irinotecan、Folinic acid、5-FU

登记的停止原因（原文）：Funding was withdrawn

Managing Chronic Tendon Pain by Metformin

药物 / 成分：Metformin、Placebo

登记的停止原因（原文）：The study funding has ended.

A Study of ASP1012 in Adults With Solid Tumors

药物 / 成分：ASP1012、Pembrolizumab

登记的停止原因（原文）：Due to strategic decision made by the sponsor the study was terminated

A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of TQC3302 Inhalation Spray in Healthy Adult Subjects

药物 / 成分：TQC3302 inhalation spray、TQC3302 inhalation spray+Tiotropium bromide and olodaterol hydrochloride inhalation spray +Budesonide Powder for Inhalation、Tiotropium bromide and olodaterol hydrochloride inhalation spray +Budesonide Powder for Inhalation+ TQC3302 inhalation spray、Budesonide Powder for Inhalation+ TQC3302 inhalation spray+ Tiotropium bromide and olodaterol hydrochloride inhalation spray

登记的停止原因（原文）：This study shall be terminated as a result of strategic adjustments to the company-sponsored research and development of TQC3302 Inhalation Spray.

A Study of Xeloda (Capecitabine) in Combination With Avastin + Short Course Chemotherapy in Patients With Metastatic Colorectal Cancer

药物 / 成分：capecitabine [Xeloda]、capecitabine [Xeloda]、bevacizumab [Avastin]、oxaliplatin

Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency

药物 / 成分：Carboplatin、Docetaxel、Laboratory Biomarker Analysis、Rucaparib Camsylate

登记的停止原因（原文）：Terminated due to insufficient funding

Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)

药物 / 成分：Acapatamab、Enzalutamide、Abiraterone、AMG 404

登记的停止原因（原文）：Amgen made a business decision to discontinue all AMG 160 clinical trials. This decision is not related to safety.

A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes

药物 / 成分：Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®、Colecalciferol 2000 IU、Placebo

登记的停止原因（原文）：Stopped for futility.

A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer

药物 / 成分：Nivolumab-relatlimab FDC、Regorafenib、TAS-102

Effect of Nortriptyline on Abdominal Pain/Discomfort and Quality of Life in Patients With Nonulcer Dyspepsia

药物 / 成分：Nortriptyline、Placebo

登记的停止原因（原文）：Not enough participants - only 5 since the study started