专业监测看板

Open-label Study to Evaluate Metreleptin in Children Under 6 Years of Age With Generalised Lipodystrophy

药物 / 成分：Metreleptin

登记的停止原因（原文）：This clinical trial was closed early due to no longer being a requirement to the European Medicines Agency.

ALEctinib for the Treatment of Pretreated RET-rearranged Advanced Non-small Cell Lung Cancer

药物 / 成分：Alectinib

登记的停止原因（原文）：Low recruitment rate

A Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

药物 / 成分：Patidegib Topical Gel, 2%、Patidegib Topical Gel, Vehicle

登记的停止原因（原文）：Terminated early due to low blinded event rate

Sintilimab for the Treatment of Locally Advanced, Metastatic, or Recurrent Angiosarcoma, the SiARa Cancer Study

药物 / 成分：Quality-of-Life Assessment、Sintilimab

登记的停止原因（原文）：PI request, \<75% participation

Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients With Active Nr-axSpA

药物 / 成分：JS005、Placebo

登记的停止原因（原文）：Company research and development strategy adjustment, decided to study temporarily

Study of Elacestrant in Combination With Onapristone in Patients With Advanced or Metastatic Breast Cancer

药物 / 成分：Elacestrant、Onapristone

登记的停止原因（原文）：Sponsor decision to discontinue onapristone development.

Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS

药物 / 成分：MT-1186、Placebo

登记的停止原因（原文）：Futility was met.

CD40L Antagonism in Rheumatoid Arthritis (RA)

药物 / 成分：Placebo for VIB4920、VIB4920 with TNFi、VIB4920 without TNFi

登记的停止原因（原文）：The study is being closed early due to insufficient participant enrollment across study sites.

Geisinger Antibiotic Allergy Pilot Program: Assess and Address

药物 / 成分：Amoxicillin

登记的停止原因（原文）：PI does not wish to proceed due to a different clinical decision tool becoming available

A Study to Evaluate the Pharmacokinetics and Safety of Loncastuximab Tesirine in Participants With Relapsed or Refractory Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma With Hepatic Impairment (LOTIS-10)

药物 / 成分：Loncastuximab Tesirine

登记的停止原因（原文）：This decision to close the study was made following interactions with regulatory authorities and in consideration of the challenges associated with this patient population. No safety information contributed to this decision.

What is Optimal Post-operative Prophylactic Therapy in Irradiated Breasts Undergoing Repeat Surgery

药物 / 成分：TMP-SMX DS、ciNPT dressing

登记的停止原因（原文）：Logistical Issues

IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches

药物 / 成分：Ferric Carboxymaltose、Ferrous Sulfate

登记的停止原因（原文）：Post-discharge low follow-up (\<50%) rates.

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Drug Levels of AR-LDD (BMS-986365) in Healthy Adult Male Participants

药物 / 成分：BMS-986365、Itraconazole、Rifampin

登记的停止原因（原文）：Business objectives have changed

Docetaxel, Cisplatin and Fluorouracil in Treating Patients With Previously Untreated Stage II-IV Nasal Cavity and Paranasal Sinus Cancer

药物 / 成分：Carboplatin、Chemoradiotherapy、Cisplatin、Definitive Surgical Resection

登记的停止原因（原文）：\<75% participation

Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma

药物 / 成分：Metformin XR、Dexamethasone

登记的停止原因（原文）：Recruitment difficulties due to more attractive competing studies.

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Adults With Solid Malignancies

药物 / 成分：zamzetoclax、Docetaxel、sacituzumab govitecan-hziy

登记的停止原因（原文）：Sponsor decision to terminate

A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients

药物 / 成分：TCD601

登记的停止原因（原文）：The Sponsor has decided to terminate study early due to significant enrolment challenges since restarting the study in Dec 2025. The Sponsor is concerned that the study is not feasible and ultimately the objectives of the study cannot be met.

Tiotropium/Salmeterol Inhalation Powder in COPD

药物 / 成分：Tiotropium/Salmeterol、Salmeterol、Placebo、Tiotropium

Phase II, Open Label, Single Arm Study of SAR302503 In Myelofibrosis Patients Previously Treated With Ruxolitinib

药物 / 成分：SAR302503

Multimodal Imaging Assessment of the Inflammatory Atheromatous Plaque

药物 / 成分：68Ga-NODAGA-RGD PET/CT

登记的停止原因（原文）：studdy stopped because of patient recruitment issues