专业监测看板

Immunotherapy Based on Tumor Associated Antigen-specific Immune Effector Cells

药物 / 成分：Engineered Immune Cells

Immunity and Safety of Covid-19 Synthetic Minigene Vaccine

药物 / 成分：Injection and infusion of LV-SMENP-DC vaccine and antigen-specific CTLs

Safety and Immunity of Covid-19 aAPC Vaccine

药物 / 成分：Pathogen-specific aAPC

Open-Label Rollover Study for Continuing Valbenazine Administration for the Treatment of Chorea Associated With Huntington Disease

药物 / 成分：Valbenazine

登记的停止原因（原文）：Sponsor Decision

4SCAR-CD44v6 T Cell Therapy Targeting Cancer

药物 / 成分：CD44v6-specific CAR gene-engineered T cells

NGS-MRD Assessment of Combination Immunotherapies Targeting T-ALL

药物 / 成分：Antigen-specific T cells CAR-T/CTL and DCvac

PSMA/CD70 Bi-specific CAR-T Cell Therapy

药物 / 成分：bi-4SCAR PSMA/CD70 T cells

KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer

药物 / 成分：KN046、regorafenib

登记的停止原因（原文）：The study was stopped early due to lack of efficacy.

Molecular Residual Disease (MRD) Guided Adjuvant ThErapy in Renal Cell Carcinoma (RCC)

药物 / 成分：Pembrolizumab injection

登记的停止原因（原文）：Loss of funding

Phase 2 Study of SAR444656 in Adult Participants With Moderate to Severe Atopic Dermatitis

药物 / 成分：SAR444656 (KT-474)、Placebo

登记的停止原因（原文）：Sponsor decision. Not related to safety concern.

Dupilumab De-escalation in Pediatric Atopic Dermatitis

药物 / 成分：Dupilumab - Discontinuation、Dupilumab - Dose Reduction、Dupilumab - Standard Dose

登记的停止原因（原文）：Poor accrual

Long-term Extension of GTX-102 in Angelman Syndrome

药物 / 成分：GTX-102

登记的停止原因（原文）：Lack of efficacy

Gemcitabine/Cisplatin Plus Cemiplimab With or Without Fianlimab in Localized Muscle-invasive Bladder Cancer (NeoSTOP-IT)

药物 / 成分：Gemcitabine、Cisplatin、Cemiplimab、Fianlimab

登记的停止原因（原文）：Change in standard of care treatment for muscle-invasive bladder cancer

Phase 3 Efficacy and Safety Study of GTX-102 in Pediatric Subjects With Angelman Syndrome (AS)

药物 / 成分：GTX-102、Sham-LP

登记的停止原因（原文）：Lack of efficacy

A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

药物 / 成分：No intervention、GTX-102

登记的停止原因（原文）：Lack of efficacy

NG2 and DLL3 CAR-T Cells Targeting Melanoma

药物 / 成分：NG2 and DLL3 CAR-T cells

FANCA Gene Transfer for Fanconi Anemia Using a High-safety, High-efficiency, Self-inactivating Lentiviral Vector

药物 / 成分：Gene-modified autologous stem cells

A Nutritional Supplement to Support People With Non-small Cell Lung Cancer

药物 / 成分：Nutritional supplement、Placebo

登记的停止原因（原文）：Unreliable supply of investigational product.

Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU)

药物 / 成分：IVUS、Continued Compression Therapy/Stockings

登记的停止原因（原文）：The study was stopped due to ongoing enrollment challenges.

Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer

药物 / 成分：Acupressure Therapy、Best Practice、Biospecimen Collection、Questionnaire Administration

登记的停止原因（原文）：Study closed per SRC Low Accrual Policy.