专业监测看板

Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF

药物 / 成分：Multiple standard of care antibiotics for appendicitis, at physicians' discretion、Multiple standard of care antibiotics for appendicitis, at physicians' discretion

登记的停止原因（原文）：Not feasible to complete trial due to low enrollment rate. Enrollment terminated and inadequately powered to achieve statistical significance on primary and secondary study outcomes.

ZN-c3 + Gemcitabine in Pancreatic Cancer

药物 / 成分：Zentalis、Gemzar

登记的停止原因（原文）：Study stopped early due to reaching the minimum number of DLTs required for halting the study due to toxicity.

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

药物 / 成分：vepdegestrant、Samuraciclib

登记的停止原因（原文）：Enrollment was permanently closed for strategic business reasons after 11 participants enrolled in Ph1b. The decision was not related to safety, efficacy, benefit-risk, or participant welfare. The planned Ph2 and DDI components were not initiated.

A Phase 1 Trial of ADI-270 in ccRCC

药物 / 成分：ADI-270、Fludarabine、Cyclophosphamide

登记的停止原因（原文）：Sponsor decision

A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas

药物 / 成分：BI 765049

登记的停止原因（原文）：Sponsor decision

A Study to Evaluate Efficacy and Safety of IBI356 in Participants With Moderate to Severe Atopic Dermatitis

药物 / 成分：Dupilumab、Placebo、IBI356

登记的停止原因（原文）：Sponsor Decision

Efficacy and Safety of Xinyi Powder in Patients With Allergic Rhinitis and the Lung Deficiency and Cold Syndrome

药物 / 成分：Xinyi Powder、Xinyi Powder placebo

登记的停止原因（原文）：Recruitment was stopped before the planned sample size was reached because the investigational product reached the end of its shelf life. The decision to stop recruitment was unrelated to interim efficacy or safety findings.

Premotor Cortex: A New Target for Stroke Motor Rehabilitation

药物 / 成分：rTMS Over Contralateral Hemisphere of Premotor Cortex、rTMS Over Ipsilateral Hemisphere of Premotor Cortex、Control 1: rTMS Timed 400 ms After Movement-related EMG、Control 2: rTMS Over the Somatosensory Cortex

登记的停止原因（原文）：Study was suspended pending additional funding to continue participant recruitment and was ultimately terminated in 2024.

Trident II Tritanium Acetabular Shell Outcomes Study

药物 / 成分：Trident II Tritanium Acetabular Shell

登记的停止原因（原文）：Study terminated due to insufficient longitudinal patient follow-up, limiting the ability to meet study objectives. Regulatory requirements can be satisfied using alternate data sources. No product safety concerns prompted termination.

Burst Spinal Cord Stimulation (Burst-SCS) Study

药物 / 成分：Burst-SCS、Sham SCS

登记的停止原因（原文）：The study was terminated early due to data quality concerns and protocol integrity issues involving inadequate sham stimulation parameters and compromised participant blinding.

Waterjet Prostate Ablation

药物 / 成分：Aquablation

登记的停止原因（原文）：Equipment is not available

Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes

药物 / 成分：Standardized Dinner、Premeal exercise

登记的停止原因（原文）：Poor accrual and lack of funding

Haemostatic Gel Prophylaxis for Post Duodenal Endoscopic Resection Bleeding

药物 / 成分：duodenal mucosectomy、ampullectomy

登记的停止原因（原文）：The sponsor, in consultation with the research team, has decided to terminate the study early. Unfortunately, there have been no new enrollments since October 2025.

Efficacy and Safety of Almonertinib Combined With Recombinant Human Endostatin in the Treatment of Stage IIIB-IV Non-small Cell Lung Cancer

登记的停止原因（原文）：The study was terminated early due to slow participant accrual. Enrollment targets could not be met within a feasible timeframe. The decision was not related to any safety concerns.

Safety and Efficacy of RashEndZ Wound Aeration Technology

药物 / 成分：Dynamic Oxygen Skin Therapy (DOST)、Standard Wound Care

登记的停止原因（原文）：Enrollment challenges, limited sponsor resources, and a smaller than expected eligible patient population.

Selinexor in Myelofibrosis Refractory or Intolerant to JAK1/2 Inhibitors

药物 / 成分：Selinexor

登记的停止原因（原文）：PI and Sponsor decision. Accrual was low and there was sufficient data to detect a response.

DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery

药物 / 成分：Tranexamic Acid

登记的停止原因（原文）：Upon the Data Safety Monitoring Board review of the interim analysis (75% of participants have finished their follow-up) on November 17, 2023, they made a recommendation to stop recruitment into the trial.

Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination

药物 / 成分：MCLA-129、Osimertinib、Chemotherapy

登记的停止原因（原文）：The Sponsor terminated the trial early for strategic business reasons. This isn't related to any safety/efficacy/clinical activity/benefit-risk concern with petosemtamab. Ongoing participants will have access to treatment outside of this trial.

A Study of ES104 in Patients With Metastatic Colorectal Cancer

药物 / 成分：ES104、ES104、ES104

登记的停止原因（原文）：Sponsor's development strategy adjustment.

Short Terms Effects of Medial Branch Block vs Para-spinal Muscle Injection in Patients With Non-specific CLBP

药物 / 成分：Medial branch block in one side、paravertebral deep intramuscular (PDI) injection